Re-activation of bovine tuberculosis in a patient treated with infliximab

Re-activation of bovine tuberculosis in a patient treated with infliximab.

Treatment with tumour necrosis factor-alpha inhibitors increases the risk of tuberculosis (TB). Screening for latent TB infection (LTBI) and prophylactic treatment has become mandatory. A 79-yr-old female with a history of severe erosive sero-positive rheumatoid arthritis was screened for LTBI before initiation of treatment with infliximab. The tuberculin skin test (TST) was negative, chest rad...

Reactivation of Bovine Tuberculosis in Patient Treated with Infliximab, Switzerland

1. Nattermann H, Horsch F. The Corynebacterium pyogenes infection in cattle. I. Incidence of the pathogen [in German]. Arch Exp Veterinarmed. 1977;31:405–13. 2. Ide A, Decostere A, Stuer P, Stuer E, De Laere A, Verlinde T, et al. Arcanobacterium pyogenes spondylodiscitis in a veterinary surgeon: plea for cooperation between medical and veterinary microbiologists in identification of causal agen...

Development of tuberculosis in a patient treated with infliximab who had received prophylactic therapy with isoniazid.

Atypical cutaneous tuberculosis in a patient with rheumatoid arthritis treated with infliximab.

Sir, Anti-tumour necrosis factor alpha (TNF-α) agents, such as infliximab, adalimumab and etanercept, are remarkably effective in the treatment of rheumatoid arthritis (RA), Crohn's disease and psoriasis vulgaris (1–4). Recent case reports have described the treatment of hidradenitis suppurativa (5) and acne conglobata (6) with infliximab. Regardless of the dramatic improvement in symptoms, it ...

Exacerbation of atopic dermatitis in a patient treated with infliximab.

in the literature on the use of imiquimod in EMPD, found complete remission of the disease in 21 of the 27 reported cases (78%). The factors that influence the success or failure of imiquimod therapy in this setting have not yet been clearly established. Factors that might explain the variability of response to treatment include the size of the lesion, its variable thickness in different areas,...